A9630
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A9630
Sigma
4-Androstene-3,17-dione
≥98%
| Synonym: | Androstenedione |
| CAS Number: | 63-05-8 |
| Linear Formula: | C19H26O2 |
| Molecular Weight: | 286.41 |
| Beilstein Registry Number: | 2059239 |
| EC Number: | 200-554-5 |
| MDL number: | MFCD00003615 |
| PubChem Substance ID: | 24278247 |
Description
| Biochem/physiol Actions | Testosterone precursor and metabolite with androgenic activity; may increase the risk of prostate or pancreatic cancer. |
Properties
| assay | ≥98% |
| drug control | USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada |
| mp | 170-171 °C(lit.) |
| Gene Information | human ... HSD17B3(3293) |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | BV8150000 |
References
| reference | Provost, P.R., Androgen formation and metabolism in the pulmonary epithelial cell line A549: expression of 17β-hydroxysteroid dehydrogenase type 5 and 3α-hydroxysteroid dehydrogenase type 3. Endocrinology 141, 2786, (2000) Abstract |
| O'Shaughnessy, P.J., Localization of 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology 141, 2631, (2000) Abstract | |
| Hagemeyer, C.E., et al., Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: a crucial role for androstenedione. J. Neurosci. 60, 106-115, (2000) | |
| Merck | Merck 13,643 |
| Beilstein | Beil. 7,IV,2381 |
| Corp MSDS 1, 263:B / FT-IR 2 (3), 4236:B / FT-NMR 1 (3), 588:A / RegBook 1 (2), 2865:G / Sigma FT-IR 1 (1), 1196:B / Structure Index 1, 459:D:1 |
